来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
天天狠天天透天干天天怕∴|嫩草影院在线观看网站
Mouse Anti-DDR2/CD167b/BF647 Conjugated antibody (bsm-51147M-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-51147M-BF647
英文名稱1 Mouse Anti-DDR2/CD167b/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的小鼠抗盤狀結(jié)構(gòu)域受體蛋白2單克隆抗體
別    名 DDR 2; DDR2; ; DDR 2; CD167b antigen; Cell migration inducing protein 20; Discoidin domain containing receptor 2; Discoidin domain receptor 2; Discoidin domain receptor family member 2v Hydroxyaryl protein kinase; MIG20a; Migration inducing gene 16 protein; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 3v NTRKR 3; NTRKR3v Receptor protein tyrosine kinase TKTv Receptor related 3; TKTv TYRO 10; TYRO10; Tyrosine kinase receptor related to neurotrophic TRK; Tyrosine protein kinase TYRO 10; Tyrosine protein kinase TYRO10; Tyrosylprotein kinase; DDR2_HUMAN; Discoidin domain-containing receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; CD167b.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 心血管  神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 3E5
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDR2/CD167b
亞    型 IgG1
純化方法 affinity purified by Protein G
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DDR 2; DDR2; ; DDR 2; CD167b antigen; Cell migration inducing protein 20; Discoidin domain containing receptor 2; Discoidin domain receptor 2; Discoidin domain receptor family member 2v Hydroxyaryl protein kinase; MIG20a; Migration inducing gene 16 protein; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 3v NTRKR 3; NTRKR3v Receptor protein tyrosine kinase TKTv Receptor related 3; TKTv TYRO 10; TYRO10; Tyrosine kinase receptor related to neurotrophic TRK; Tyrosine protein kinase TYRO 10; Tyrosine protein kinase TYRO10; Tyrosylprotein kinase; DDR2_HUMAN; Discoidin domain-containing receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; CD167b.

Function:
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

Subunit:
Binds hydroxyproline-rich sequence motifs in fibrillar, glycosylated collagen, such as the GQOGVMGFO motif, where O stands for hydroxyproline. Interacts with SRC. Interacts (tyrosine phosphorylated) with SHC1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Detected in osteocytes, osteoblastic cells in subchondral bone, bone lining cells, tibia and cartilage. Detected at high levels in heart and lung, and at low levels in brain, placenta, liver, skeletal muscle, pancreas, and kidney.

Post-translational modifications:
N-glycosylated.
Tyrosine phosphorylated in response to collagen binding. Phosphorylated by SRC; this is required for activation and subsequent autophosphorylation on additional tyrosine residues.

DISEASE:
Defects in DDR2 are the cause of spondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL) [MIM:271665]. A bone disease characterized by short-limbed dwarfism, a narrow chest with pectus excavatum, brachydactyly in the hands and feet, a characteristic craniofacial appearance and premature calcifications. The radiological findings are distinctive and comprise short long bones throughout the skeleton with striking epiphyses that are stippled, flattened and fragmented and flared, irregular metaphyses. Platyspondyly in the spine with wide intervertebral spaces is observed and some vertebral bodies are pear-shaped with central humps, anterior protrusions and posterior scalloping.

Similarity:
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Contains 1 F5/8 type C domain.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 4921 Human

Entrez Gene: 18214 Mouse

Entrez Gene: 685781 Rat

Omim: 191311 Human

SwissProt: Q16832 Human

SwissProt: Q62371 Mouse

Unigene: 275757 Human

Unigene: 593833 Human

Unigene: 229249 Mouse

Unigene: 224678 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
三男一女做2爱A片免费视频| 国产成人久久婷婷精品流白浆| 亚洲a∨一区二区三区性色| 亚洲国产AV一区二区三区| 又爽又黄又无遮挡动漫| 驯服人妻HD中字日本| 亲爱的老师4中字韩国电影 | 精品久久久久久综合日本| 少妇AAA级久久久无码精品片| 日韩一区二区三区精品| H动漫在线观看| 精品久久久久久中文字幕| 国产精品人成视频免费播放| 野花高清完整版免费观看视频电视| 牛牛精品强奸乱奸视频正| 97久久精品亚洲中文字幕无码| 性色AV浪潮AV色欲AV一区| 亚洲A∨无码天堂在线观看| 一本一道久久综合狠狠老 | 国产棈品久久嫩一区| 免费A级毛片AV无码| 96色色在线| 啊灬啊灬啊灬快灬深用力| 国产高清制服一区| AV无码精品一区二区三区四区| 蝴蝶伊人中文综合娱乐网| 国产免费观看久久黄AV片| 精品国产va久久久久久久| 精品久久久久久视频| 国产精品区一区二区三区 | 精品久久久久久久一区二区2| 全部免费毛片av无码| 猫咪成人一二三区日韩国产| 97人人模人人爽人人少妇| 国产乱子伦精品无码专区| 无码精品一区二区三区| 乔家的儿女电视剧全集免费播放 | 丰满少妇被猛烈高清播放| 免费av在线| 天天av天天av天天透| 国产精品宅男擼66M3U8|