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Mouse Anti-FASN/Gold Conjugated antibody (bsm-51155M-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bsm-51155M-Gold
英文名稱1 Mouse Anti-FASN/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的小鼠抗脂肪酸合成酶單克隆抗體
別    名 fatty acid synthase; FASN; FAS; FA Synthase 1; MGC14367; MGC15706; OA-519; Fatty acid synthase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; Enoyl-[acyl-carrier-protein] reductase; Oleoyl-[acyl-carrier-protein] hydrolase; FAS_MHUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  合成與降解  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號(hào) 2C5
交叉反應(yīng) (predicted: Human, Mouse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 274kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FASN
亞    型 IgM
純化方法 affinity purified by Protein AGL
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
FASN (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis. FAS is a target for SREBP and is upregulated by LXR activation; it is also one of the accepted markers for insulin resistance, SREBP and LXR activation.

Function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

Subunit:
Homodimer which is arranged in a head to tail fashion.

Subcellular Location:
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Ubiquitous. Prominent expression in brain, lung, and liver.

Similarity:
Contains 1 acyl carrier domain.

Database links:

Entrez Gene: 2194 Human

Entrez Gene: 14104 Mouse

Entrez Gene: 50671 Rat

Entrez Gene: 281152 Cow

Omim: 600212 Human

SwissProt: P12276 Chicken

SwissProt: Q71SP7 Cow

SwissProt: P49327 Human

SwissProt: P19096 Mouse

SwissProt: P12785 Rat

Unigene: 8951 Chicken

Unigene: 30099 Cow

Unigene: 83190 Human

Unigene: 236443 Mouse

Unigene: 9486 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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