来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
欧美人与物VIDEOS另类|久久人人97超碰A片精品|欧美日韩国产在线精品
Rabbit Anti-Neutrophil Elastase/PE-Cy3 Conjugated antibody (bs-23549R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-23549R-PE-Cy3
英文名稱1 Rabbit Anti-Neutrophil Elastase/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的中性粒細(xì)胞彈性蛋白酶ELANE抗體
別    名 Bone Marrow Serine Protease; ELA 2; ELA2; ELANE; Elastase 2; Elastase-2; Elastase 2 neutrophil; Elastase neutrophil expressed; Elastase-2; ELNE_HUMAN; GE antibody Granulocyte derived elastase; HLE; HNE; Human leukocyte elastase; Leukocyte elastase; Leukocyte Elastase Precursor; Medullasin; NE; Neutrophil elastase; Neutrophill elastase; PMN E; PMN Elastase; Polymorphonuclear elastase; SCN1; Serine protease; SERP1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neutrophil Elastase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, May 2009].

Function:
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.

Subunit:
Interacts with NOTCH2NL.

Tissue Specificity:
Bone marrow cells.

DISEASE:
Defects in ELANE are a cause of cyclic haematopoiesis (CH) [MIM:162800]; also known as cyclic neutropenia. CH is an autosomal dominant disease in which blood-cell production from the bone marrow oscillates with 21-day periodicity. Circulating neutrophils vary between almost normal numbers and zero. During intervals of neutropenia, affected individuals are at risk for opportunistic infection. Monocytes, platelets, lymphocytes and reticulocytes also cycle with the same frequency.
Defects in ELANE are the cause of neutropenia severe congenital autosomal dominant type 1 (SCN1) [MIM:202700]. SCN1 is a disorder of hematopoiesis characterized by a maturation arrest of granulopoiesis at the level of promyelocytes with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/l and early onset of severe bacterial infections.

Similarity:
Belongs to the peptidase S1 family. Elastase subfamily. Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 1991 Human

Entrez Gene: 50701 Mouse

Omim: 130130 Human

SwissProt: P08246 Human

SwissProt: Q3UP87 Mouse

Unigene: 99863 Human

Unigene: 262194 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
激情五月亚洲色图| 狠狠做深爱婷婷久久综合一区 | 99久久无色码中文字幕免费| 干屁股大奶视频| 亚洲腹肌男啪啪网站男同| 亚洲大尺度无码专区尤物 | 777米奇色狠狠俺去啦| 国产成品精品午夜视频| 88久久精品无码一区二区毛片| A级毛片无码免费真人久久| 国产,日韩,欧美在线| 亚洲成AV人片迅雷BT下载Q链接| 好吊妞| 国产性猛交╳XXX乱大交| 9999久久久久老熟妇二区| 伊人情人综合网| 隔着内裤揉搓她的花蒂H漫画| 尤物AV网址在线观看| 亚洲 小说 欧美 激情 另类| 日韩av毛片一区二区三区四区| 精品国产综合成人亚洲区2022| 国产,日韩,丝袜,欧美一区| 日韩精品无码一区二区三区不卡| 亚洲人成人精品久久| 91欧美一区二区三区| 国产免费AV片在线无码免费看| 乌克兰肥妇黑毛BBW| 色婷婷av一区二区三区不卡| 又白又嫩毛又多15P| 欧美日韩精品久久久免费观| 午夜无码电影888不卡| 西班牙女郎完整版在线播放 | 午夜精品久久久久久99影视| 又大又粗又爽A级毛片免费看| 熟女aaa一区二区午夜| 人妻在厨房被色诱 中文字幕| 久久久亚洲精品无码| 国产AV无码专区亚洲AV| AV无码免费一区二区三区| 欧美无人区码SUV| 久久老子午夜精品无码|